| 应用近红外光谱技术对胶质瘤大鼠射频热疗的实时在位监测研究 |
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| 引用本文： | 刘华亭,杨天明,钱志余,郭凯,张立国. 应用近红外光谱技术对胶质瘤大鼠射频热疗的实时在位监测研究[J]. 东南大学学报(医学版), 2011, 30(3): 436-440. DOI: 10.3969/j.issn.1671-6264.2011.03.009 |
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| 作者姓名： | 刘华亭 杨天明 钱志余 郭凯 张立国 |
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| 作者单位： | 1. 东南大学附属中大医院,神经外科,江苏,南京,210009
2. 南京航空航天大学,生物医学工程系,江苏,南京,210016 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 目的:观察近红外光谱(near-infrared spectroscopy,NIRS)光学参数在胶质瘤射频热疗术中的变化规律,探讨利用NIRS对胶质瘤射频热疗进行实时监测的可行性.方法:将C6胶质瘤细胞注入大鼠脑右侧尾状核建立胶质瘤大鼠模型;在不同时间、温度下对荷瘤大鼠进行靶向毁损,观察并记录肿瘤组织射频加热时靶点的N...
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| 关 键 词： | 近红外光谱 优化散射系数 胶质瘤 射频毁损 大鼠 |
In vivo and real-time monitoring research of rats with glioma in radiofreqency ablation by near-infrared spectroscopy technology |
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| LIU Hua-ting,YANG Tian-ming,QIAN Zhi-yu,GUO Kai,ZHANG Li-guo. In vivo and real-time monitoring research of rats with glioma in radiofreqency ablation by near-infrared spectroscopy technology[J]. Journal of Southeast Univ: Medical Sci Ed, 2011, 30(3): 436-440. DOI: 10.3969/j.issn.1671-6264.2011.03.009 |
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| Authors: | LIU Hua-ting YANG Tian-ming QIAN Zhi-yu GUO Kai ZHANG Li-guo |
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| Affiliation: | LIU Hua-ting1,YANG Tian-ming1,QIAN Zhi-yu2,GUO Kai1,ZHANG Li-guo1(1.Department of Neurosurgery,Zhongda Hospital,Southeast University,Nanjing 210009,China,2.Department of Biomedical Engineering,Nanjing University of Aeronautics and Astronautics,Nanjing 210016,China) |
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| Abstract: | Objective: To explore the feasibility of using near-infrared spectroscopy(NIRS) technology to monitor real-time in the radiofreqency ablation technology of the rats with glioma and to observe the process of changes in the optical parameters.Methods: Injecting C6 glioma cells into the right caudate nucleus of rat brain to establish animal models.Target destruction was performed in NIRS monitoring in different time and temperature.The changes of optical parameters,the reduced scattering coefficient in particu... |
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| Keywords: | near-infrared spectroscopy reduced scattering coefficient glioma radiofreqency ablation rats |
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