| 病毒感染与慢性阻塞性肺疾病的关系 |
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| 引用本文： | 惠复新,吴艳,汪家坤. 病毒感染与慢性阻塞性肺疾病的关系[J]. 实用临床医药杂志, 2011, 15(23) |
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| 作者姓名： | 惠复新 吴艳 汪家坤 |
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| 作者单位： | 南京医科大学附属无锡人民医院呼吸科,江苏无锡,214000 |
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| 摘 要： | 目的观察慢性阻塞性肺疾病(COPD)患者病毒感染状况,探讨其与COPD的关系。方法选择268例慢性阻塞性肺疾病急性加重(AECOPD)患者(A组),92例COPD稳定者(B组),76例正常者(C组)。分别检测呼吸道合胞病毒(RSV)、单纯疱疹病毒(HSV)、腺病毒(ADV)、巨细胞病毒(CMV)特异性抗体IgM及IgG水平,并进行比较。结果 A组的IgM阳性率(20.5%)明显高于B组(3.3%)及C组(3.9%);A组(74.2%)及B组(70.5%)的IgG阳性率均明显高于C组(31.6%)。A组患者病毒感染情况较重,IgM阳性率依次为ADV>RSV>CMV>HSV,IgG阳性率依次为HSV>CMV>ADV>RSV。结论病毒感染是COPD急性加重的重要因素,病毒的反复及潜在感染参与了COPD病情的进展过程。
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| 关 键 词： | 阻塞性肺疾病 病毒 抗体 |
Correlation between virus infections and chronic obstructive pulmonary disease |
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| HUI Fu-xin , WU Yan , WANG Jia-kun. Correlation between virus infections and chronic obstructive pulmonary disease[J]. Journal of Clinical Medicine in Practice, 2011, 15(23) |
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| Authors: | HUI Fu-xin WU Yan WANG Jia-kun |
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| Abstract: | Objective To explore the relationship between virus infections and chronic obstructive pulmonary disease(COPD).Methods Serum samples from 268 patients with acute exacerbation of COPD(group A),92 patients with stable COPD(group B),and 76 healthy subjects(group C) were tested for specific IgM and IgG of RSV,ADV,HSV and CMV.Results The positive IgM rates of Group A(20.5%) were significantly higher than those of group B(3.3%) and C(3.9%).The positive rates of IgM were significantly higher in group A(74.2%) and ... |
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| Keywords: | chronic obstructive pulmonary disease virus antibody |
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