| 龟鹿二仙胶颗粒对D-半乳糖所致衰老大鼠抗氧化能力的影响 |
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| 引用本文： | 王树鹏,刘书宇. 龟鹿二仙胶颗粒对D-半乳糖所致衰老大鼠抗氧化能力的影响[J]. 中药药理与临床, 2011, 0(1): 1-3 |
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| 作者姓名： | 王树鹏 刘书宇 |
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| 作者单位： | 辽宁中医药大学; |
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| 摘 要： | 目的:研究龟鹿二仙颗粒对D-半乳糖所致衰老大鼠抗氧化能力的影响。方法:W istar雄性大鼠随机分组,正常对照组皮下注射生理盐水,模型对照组和各给药防治组大鼠均每日皮下注射D-半乳糖1.2g/kg,同时各防治组灌服龟鹿二仙颗粒或维生素E,连续造模给药16周,16周末各组大鼠腹主动脉采血分离血清,并取心、肝、肾组织冰浴匀浆,检测血清、组织匀浆超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性和丙二醛(MDA)的含量,以评价龟鹿二仙胶颗粒对D-半乳糖所致衰老大鼠抗氧化功能影响。结果:与正常对照组相比,模型对照组血清、心、肝、肾匀浆SOD、GSH-Px活力显著降低,MDA含量显著增高。与模型对照组相比,各给药防治组SOD、GSH-Px活力显著增高,MDA含量显著降低。结论:龟鹿二仙胶颗粒对D-半乳糖所致衰老大鼠具有显著提高抗氧化能力的作用。
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| 关 键 词： | 龟鹿二仙胶颗粒 抗氧化 超氧化物歧化酶 谷胱甘酞过氧化物酶 丙二醛 |
Turtle and deer antlers rubber particles on D-galactose induced aging antioxidant function in rats |
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| Wang Shupeng,Liu Shuyu. Turtle and deer antlers rubber particles on D-galactose induced aging antioxidant function in rats[J]. Pharmacology and Clinics of Chinese Materia Medica, 2011, 0(1): 1-3 |
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| Authors: | Wang Shupeng Liu Shuyu |
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| Affiliation: | Wang Shupeng,Liu Shuyu (Liaoning University of Traditional Chinese Medicine,Shenyang 110032) |
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| Abstract: | Objective: To study the turtles and deer antlers particles on D-galactose induced aging rat anti-oxidation function.Methods: Male Wistar rats were randomly divided into different groups.Subcutaneous injection of normal saline control group,model group and treatment group daily subcutaneous injection of D-galactose 1.2g/kg,while the treatment group fed with turtle and deer antlers particles or vitamin E,normal control group and model control group were administered by normal saline for 16 weeks,after 16-week... |
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