| 动脉粥样硬化易损斑块动物模型研究 |
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| 引用本文： | 王建辉,李磊,刘建勋. 动脉粥样硬化易损斑块动物模型研究[J]. 中药药理与临床, 2011, 0(4): 89-92 |
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| 作者姓名： | 王建辉 李磊 刘建勋 |
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| 作者单位： | 中国中医科学院西苑医院; |
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| 基金项目： | 国家科学自然基金(30830118); 国家科技重大专项:重大新药创制(2009zx09301-005;2009zx09303-003) |
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| 摘 要： | 动脉粥样硬化(atherosc lerosis,AS)斑块破裂及血栓形成是临床心脑血管事件的主要原因。然而,易损斑块及斑块破裂目前尚无理想的动物模型,因此,寻找到一种理想的易损斑块动物模型,对于易损斑块研究和临床治疗都是迫切需要的。本文就易损斑块动物模型的研究现状做一简要概述。
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| 关 键 词： | 动脉粥样硬化 易损斑块 动物模型 |
The model of vulnerable plaque in atherosclerotic:a literature review |
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| Wang Jianhui,Li Lei,Liu JianxunExperimental Research Center,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing ). The model of vulnerable plaque in atherosclerotic:a literature review[J]. Pharmacology and Clinics of Chinese Materia Medica, 2011, 0(4): 89-92 |
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| Authors: | Wang Jianhui Li Lei Liu JianxunExperimental Research Center Xiyuan Hospital China Academy of Chinese Medical Sciences Beijing ) |
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| Affiliation: | Wang Jianhui,Li Lei,Liu JianxunExperimental Research Center,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091) |
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| Abstract: | The main reason for clinical cardiovascular and cerebrovascular events is plaque rupturing and thrombosis.However,there is not perfect animal model in the vulnerable plaque and plaque rupturing.Therefore,it is exigent to find an appropriate animal model for research and clinical treatment.This article will make an overview about the vulnerable plaque animal model. |
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| Keywords: | Atherosclerosis vulnerable plaque animal model overview |
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