| HPLC法测定独一味分散片中木犀草素的含量 |
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| 引用本文： | 李瑞麟. HPLC法测定独一味分散片中木犀草素的含量[J]. 安徽医药, 2010, 14(9): 1029-1030. DOI: 10.3969/j.issn.1009-6469.2010.09.017 |
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| 作者姓名： | 李瑞麟 |
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| 作者单位： | 安徽省合肥市第一人民医院药学部,安徽,合肥,230061 |
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| 基金项目： | 安徽省第三周期临床医学特色专科基金，合肥市第二周期医学重点学科基金 |
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| 摘 要： | 目的建立独一味分散片中木犀草素的含量测定方法。方法采用高效液相色谱法,VP-ODS（4.6 mm×150 mm,5μm）;流动相：甲醇-0.4%磷酸溶液（50∶50）;流速：1.0 ml·min^-1;柱温：30℃;检测波长为350 nm。结果木犀草素线性范围为4.55-40.95 mg·L^-1,平均加样回收率为100.3%。结论本方法专属性强,快速简便,准确性高,可用于独一味分散片控制制剂质量。
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| 关 键 词： | 高效液相色谱 独一味分散片 木犀草素 |
Determination of luteolin in duyiwei dispersible tablet by HPLC |
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| LI Rui-lin. Determination of luteolin in duyiwei dispersible tablet by HPLC[J]. Anhui Medical and Pharmaceutical Journal, 2010, 14(9): 1029-1030. DOI: 10.3969/j.issn.1009-6469.2010.09.017 |
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| Authors: | LI Rui-lin |
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| Affiliation: | LI Rui-lin(Department of Pharmacy,The Third Hospital Affiliated of Anhui Medical University,Hefei,Anhui 230061) |
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| Abstract: | Aim To develop a method for determining the contents of luteolin in duyiwei dispersible tablet.Methods The analytical column was a Hypersil VP-ODS(4.6 mm×250 mm,5 μm).The mobile phase consisted of methanol-0.4%H2PO4(50∶50).The flow rate was 1.0 ml·min-1and the column temperature was 30℃.The detection wavelengths of luteolin was at 350 nm.Results The calibration curves of luteolin was in good linearity over the range from 4.55 to 40.958 mg·L-1,and the average recovery was 100.3%.Conclusion The method is simple,accurate and reproducible.It is rapid,reliable and can be used for the duyiwei dispersible tablet control. |
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| Keywords: | HPLC duyiwei dispersible tablet luteolin |
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