Screening asymptomatic adolescent males for chlamydia |
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| Institution: | 1. From St. Christopher''s Hospital, Philadelphia, Pennsylvania, USA;2. Children''s Hospital Medical Center, Cincinnati, Ohio, USA;3. Veteran''s Administration Hospital, Cincinnati, Ohio, USA;1. Global Disaster Resilience Centre, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK;2. National Dengue Control Unit, 7th Floor, Public Health Complex, Ministry of Health, Sri Lanka, 555/5, Elvitigala Mawatha, Colombo, Sri Lanka;1. Department of Obstetrics and Gynecology, Suzhou Municipal Hospital, Suzhou, 215002, P. R. China;2. Department of Obstetrics and Gynecology, the First Affiliated Hospital of University of Science and Technology of China, Hefei, 230001, P. R. China;3. Department of Obstetrics and Gynecology, Anhui Provincial Hospital affiliated to Anhui Medical University, Hefei, 230001, P. R. China;1. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Centre for Infectious Diseases, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China;2. Department of General Practice, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China;3. Department of Cardiology and Endodontics, The Stomatology Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China;1. Unit of Molecular and Nutritional Epidemiology, Institute for Cancer Research and Prevention (ISPO), Italy;2. Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy;3. Department of Infectious Disease Epidemiology, National Center for Epidemiology, Budapest, Hungary;4. Division for HIV/AIDS, STI and Blood-Borne Infections, Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany;5. South East Regional Epidemiology Unit, Health Protection Agency, London, UK;6. Swedish Institute for Communicable Disease Control, Solna, Sweden |
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| Abstract: | Ninety-seven asymptomatic 16–21-year-old sexually active adolescent males were evaluated for gonorrhea and chlamydia by culture, chlamydia enzyme immunoassay, and an analysis of a random urine sample for pyuria using centrifuged urine and urine cytometer. The incidence of gonorrhea was 5.3% and chlamydia by culture 12.3%. Immunoassay was superior in sensitivity and specificity (75% and 99%, respectively) to centrifuged urine (sensitivity 58%, specificity 92%) or urine cytometer (58% and 91%) in identifying asymptomatic chlamydia urethritis. Chlamydia enzyme immunoassay is an acceptable, more rapid, and less expensive alternative to culture. The absence of pyuria in asymptomatic males cannot be assumed to indicate the absence of a sexually transmitted disease. |
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