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The antigenic diversity of rotaviruses: Significance to epidemiology and vaccine strategies
Authors:G. M. Beards  D. W. G. Brown
Affiliation:(1) Regional Virus Laboratory and WHO Collaborating Centre for Reference and Research on Rotaviruses, East Birmingham Hospital, B9 5ST Birmingham, UK;(2) Wellcome Research Unit Christian, Medical College Hospital, Vellore, Tamil Nadu, India;(3) Present address: Virus Reference Laboratory, C.P.H.L., NW9 5HT Colindale, London
Abstract:Rotaviruses are the major cause of infantile gastroenteritis world-wide. Much antigenic diversity exists amongst them. This has important implications to diagnosis, epidemiology and vaccination strategies. The nature of this diversity is now well understood. This review outlines and discussed our current knowledge of the subject from a historical perspective.
Keywords:Rotavirus serotypes  subgroups  Vaccines  Atypical rotaviruses
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