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The Post‐mastectomy Pain Syndrome—A Systematic Review of the Treatment Modalities
Authors:Inga Magdalena Larsson MD  Jens Ahm Sørensen MD  PhD  Camilla Bille MD  PhD
Affiliation:Department of Plastic Surgery, Odense University Hospital, Odense, Denmark
Abstract:Post‐mastectomy pain syndrome (PMPS) is a chronic neuropathic pain condition, affecting many women who have undergone breast cancer surgery. The development of PMPS is complex and the treatment options are limited. In this systematic review, we have analyzed the existing treatment modalities of PMPS. Six studies on five treatments were carefully selected, critically evaluated, and presented. The treatments were: antidepressants, anti‐epileptics, topical capsaicin, and autologous fat grafting. Four of these treatments had a significant effect on PMPS. However, most of the studies had several flaws and therefore larger studies of high quality should be performed in the future.
Keywords:breast cancer  mastectomy  pain  treatment
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