| 苦楝皮的化学成分研究 |
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| 引用本文： | 颜滢,黄晨. 苦楝皮的化学成分研究[J]. 药学实践杂志, 2011, 29(4): 285-286,317 |
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| 作者姓名： | 颜滢 黄晨 |
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| 作者单位： | 衡阳市中心医院,湖南,衡阳,421001 |
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| 摘 要： | 目的研究驱虫药苦楝皮的化学成分。方法利用各种色谱方法对苦楝皮中的化学成分进行分离和纯化,并通过IR、MS、NMR等技术鉴定所得化合物的结构。结果苦楝皮中得到5个化合物,经鉴定为苦楝萜醇内酯(kulolactone,1)、苦楝萜酸甲酯(methyl kulonate,2)、salanin(3)、1-tigloyltrichilinin(4)及β-谷甾醇(5)。结论化合物4为一个新的柠檬苦素类化合物,命名为1-tigloyltrichilinin。
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| 关 键 词： | 苦楝皮 化学成分 柠檬苦素 |
| 收稿时间： | 2011-06-03 |
| 修稿时间： | 2011-06-28 |
Study on the chemical constituents of Cortex Meliae |
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| YAN Ying and HUANG Chen. Study on the chemical constituents of Cortex Meliae[J]. The Journal of Pharmaceutical Practice, 2011, 29(4): 285-286,317 |
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| Authors: | YAN Ying and HUANG Chen |
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| Affiliation: | The Central Hospital of Hengyang,Hengyang 421001,China |
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| Abstract: | Objective To study the chemical constituents of Cortex Meliae.Methods Chromatographic techniques were employed to isolate and purify the chemical constituents of Cortex Meliae.Structures of the chemical constituents were elucidated by methods of IR,MS and NMR.Results Five compounds were isolated and identified as kulolactone（1）,methyl kulonate（2）,salanin（3）,1-tigloyltrichilinin（4） and β-sitosterol（5）,respectively.Conclusion Compound 4 was a new limonoid and named as 1-tigloyltrichilinin. |
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| Keywords: | Cortex Meliae chemical constituents limonoid |
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