氯硝柳胺悬浮剂杀灭曼氏血吸虫中间宿主光滑双脐螺效果观察

目的观察氯硝柳胺悬浮剂（SCN）对光滑双脐螺的杀灭效果。方法用SCN、50%氯硝柳胺乙醇胺盐可湿性粉剂（WPN）和氯硝柳胺原药分别配制成药物有效浓度为1.000、0.500、0.250、0.125 mg/L和0.063 mg/L的溶液,在实验室浸泡光滑双脐螺成螺,计算LC50。采用上述3种剂型的氯硝柳胺分别配制成药物有效浓度为0.500、0.250、0.125、0.063mg/L和0.032 mg/L的溶液,浸泡螺卵,计算LC50。结果将成螺浸泡在SCN、WPN和氯硝柳胺溶液中,24 h LC50分别为0.218、0.218 mg/L和0.203 mg/L;48 h LC50分别为0.189、0.203 mg/L和0.189 mg/L;72 h LC50分别为0.165、0.218 mg/L和0.177 mg/L。将螺卵浸泡在SCN、WPN和氯硝柳胺溶液中,24 h LC50分别为0.153、0.173 mg/L和0.171 mg/L;48 hLC50分别为0.085、0.096 mg/L和0.155 mg/L;72 h LC50分别为0.077、0.097 mg/L和0.087 mg/L。结论SCN对光滑双脐螺成螺和螺卵均具有与WPN和原药相同的杀灭效果。

Molluscicidal effect of suspension concentrate of niclosamide against Biomphalaria glabrata, an intermediate host of Schistosoma mansoni

Objective To evaluate the molluscicidal effect of suspension concentrate of niclosamide（SCN） against Biomphalaria glabrata.Methods SCN,wettable powder of 50% niclosamide ethanolamine salt（WPN） and original niclosamide were formulated into solutions with active concentrations of 1.000,0.500,0.250,0.125 mg/L and 0.063 mg/L,respectively.The adult snails of B.glabrata were immersed in these solutions,and LC50（s） were calculated.The three preparations of niclosamide mentioned above were formulated into solutions with active concentrations of 0.500,0.250,0.125,0.063 mg/L and 0.032 mg/L,respectively.The snail eggs of B.glabrata were immersed in these solutions,and LC50（s） were calculated.Results When the adult snails were immersed in the solutions of SCN,WPN and niclosamide,LC50（s） were 0.218,0.218,0.203 mg/L for 24 h,0.189,0.203,0.189 mg/L for 48 h,0.165,0.218,0.177 mg/L for 72 h,respectively.When the snail eggs were immersed in the solutions of SCN,WPN and niclosamide,LC50（s） were 0.153,0.173,0.171 mg/L for 24 h,0.085,0.096,0.155 mg/L for 48 h,0.077,0.097,0.087 mg/L for 72 h,respectively.Conclusion The molluscicidal effect of SCN against the adult snails and snail eggs of B.glabrata is the same as WPN and niclosamide.