| 大鼠脊髓全横断损伤后不同时间的组织改变 |
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| 引用本文： | 朱俊德,余资江,刘鲜林,常傲霜.大鼠脊髓全横断损伤后不同时间的组织改变[J].山东大学学报(医学版),2011,49(1):43-47. |
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| 作者姓名： | 朱俊德 余资江 刘鲜林 常傲霜 |
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| 作者单位： | 1. 贵阳医学院基础医学院人体解剖学教研室,贵阳,550004
2. 贵阳医学院电子显微镜室,贵阳,550004 |
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| 基金项目： | 国家自然科学基金（30660189）；2009年度贵州省社会发展科技攻关计划项目（黔科合SY字［2009］3058）；贵阳医学院青年教师基金（K200761、63）资助项目。 |
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| 摘 要： | 目的 观察大鼠脊髓全横断损伤后不同时间的神经元、神经胶质及髓鞘结构的改变.方法 将60只大鼠随机分为假手术组(sham组)和脊髓损伤组(SCI组),SCI组又分为术后l d、3 d、7 d、14 d、21 d组,每组10只. SCI组行脊髓T9段全横断损伤,sham组仅行椎板切除术,分别在各时间点灌注固定后取材、制片,...
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| 关 键 词： | 脊髓损伤 神经元 神经胶质 髓鞘 组织结构 大鼠 Wistar |
| 收稿时间： | 2009-10-17 |
Structure change of complete transected spinal injury at different times in rats |
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| ZHU Jun-de,YU Zi-jiang,LIU Xian-lin,CHANG Ao-shuang.Structure change of complete transected spinal injury at different times in rats[J].Journal of Shandong University:Health Sciences,2011,49(1):43-47. |
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| Authors: | ZHU Jun-de YU Zi-jiang LIU Xian-lin CHANG Ao-shuang |
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| Institution: | ZHU Jun-de 1,YU Zi-jiang 1,LIU Xian-lin 2,CHANG Ao-shuang 2 (1.Department of Anatomy,2.Electronic Microscopy Room,Basic Medical College,Guiyang Medical University,Guiyang 550004,China) |
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| Abstract: | Objective To observe structure changes of neurons,neuroglia and myelin at different times in the rat model of complete transected spinal injury.Methods A total of 60 Wistar rats were randomly divided into the sham operation group(sham group) and the spinal cord injury group(SCI group),the SCI group was randomly subdivided into 1,3,7,14 and 21 days subgroups according to operation time,10 in each group.SCI groups rats were established at the T9 spinal cord segment,and rats of the sham group had laminectomy p... |
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| Keywords: | Spinal cord injury Neuron Neuroglia Myelin sheath Structure Rats Wistar |
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