高血压性脑干出血预后因素分析

目的探讨高血压性脑干出血预后相关的因素。方法回顾性分析57例高血压性脑干出血病人的临床资料，采用Kaplan—Meier法计算生存期及进行生存分析。以随访GOS评分为预后的判断指标，使用Fisher精确概率检验进行单因素分析，二分类Logistic回归作多冈素分析。结果单因素分析显示：入院时GCS评分、脑干血量及并发症是影响脑干出血预后的因素（P〈0．05）；其中人院时GCS评分13～15分，腑十出血量≤5ml及无并发症的病人预后较好。多因素分析显示：GCS评分和行发症是高血压性脑十出血预后相关的独立凶素（P〈0．05）。GCS评分越低，病人生存时间越短；有并发症者明显较无行发症者预后差。结论发病时GCS评分、出血量和并发症是影响病人预后的重要因素。

Prognostic factors analysis of hypertensive brainstem hemorrhage

Objective To investigate the factors related to prognosis of hypertensive brainstem hemorrhage （HBH）. Methods Clinical data of 57 patients with HBH were analyzed retrospectively. The survival analysis was performed and survival time calculated by Kaplan-Meier method. The judging index for prognosis was GOS scores during the follow-up period. The univariate analysis was performed by Fisher＇s test and multivariate analysis by Logistic regression. Results Univariate analysis revealed that the factors such as admission GCS score, hemorrhage volume and complications influenced the prognosis of HBH （P 〈 0.05）. Better prognosis was more frequently seen in patients with admission GCS scores of 13 to 15, hematoma volume no more than 5 ml and no complication. Multivariate analysis showed that admission GCS scores and complication were independent prognostic factors （P 〈 0.05）. As the admission GCS score was lower, the survival time of patients became shorter. The patients with complications had a poorer outcome than those without complication. Conclusion GCS score, hemorrhage volume and complications are important prognostic factors for HBH.