肺表面活性物质预防高危早产儿呼吸窘迫综合征的临床观察

目的探讨应用肺表面活性物质(PS)预防高危早产儿呼吸窘迫综合征(NRDS)的临床效果。方法28例高危早产儿气管内滴注单剂预防量PS,与同期未用PS的30例高危早产儿进行临床对照研究。结果治疗组在氧疗时间、机械通气时间、住院时间、重症HMD(三、四级)发病率、上机率、并发症发生率方面与对照组比较有显著性差异。结论PS预防性给药可缩短氧疗时间、机械通气时间和住院时间,减少重症HMD(三、四级)发病率,减少上机率,减少并发症,值得临床推广。

Clinic Observation on Pulmonary Surfactant to Prevent High Risk Neonatal Respiratory Distress yndr Some

Objective Probe into tile clinical effect of applying pulmonary surfactant (PS) to prevent high risk neonatal respiratory distress syndrome (NRDS). Methods 28 case oF high risk premature were instilled through their trachea with single preventing-dose of PS, then, study and compare their clinical effect withnother 30 case of high risk premature that did not use PS. Results There is distinct difference between this therapy group and comparison group on such aspect as oxygen treatment time, machine aerating time, period of being in hospital, incidence of a disease for heavy symptom HMD (grade 3-4), rate of machine treatment, and occurring rate for syndrome. Conclusions applying PS in preventive-dose can reduce the oxygen treatment time, machine aerating time and period of being in hospital, and decrease the incidence of a disease for heavy symptom HMD (grade 3-4), the rate of machine treatment, as well as the rate of machine treatment and syndrome occurring. Therefore it is worthy to promote such practice in clinic.