Hepatic fibrin-ring granulomas: a clinicopathologic study of 23 patients |
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Authors: | M Marazuela A Moreno M Yebra E Cerezo C Gómez-Gesto J A Vargas |
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Institution: | Hospital Puerta de Hierro, Madrid, Spain. |
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Abstract: | Twenty-three patients with characteristic hepatic fibrin-ring granulomas were studied. Q fever accounted for 10 cases (43%), visceral leishmaniasis for five cases (22%), boutonneuse fever for two cases (9%), and toxoplasmosis, Hodgkin's disease, and allopurinol hypersensitivity for one case each (4%). The etiology remained undetermined in three cases (13%). This report broadens the range of etiologies of hepatic fibrin-ring granulomas to include boutonneuse fever and toxoplasmosis in the differential diagnosis of ring granulomas, and it could serve as a guideline to the clinician and pathologist for the most frequent categories of disease associated with this morphologic pattern. |
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