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Leukoreduction in patients with severe pertussis with hyperleukocytosis
Authors:Oñoro Gonzalo  Salido Alberto García  Martínez Ignacio Mastro  Cabeza Beatriz  Gillén María  de Azagra Amelia Martínez
Institution:Pediatric Intensive Care Unit, Hospital Infantil Universitario Ni?o Jesús, Madrid, Spain. gonorootero@hotmail.com
Abstract:When pertussis is associated with hyperleukocytosis, mortality approaches to 80%. Immature leukocytes have been identified in pulmonary arterioles, small arteries and venules. Techniques aimed at reducing leukocyte mass might improve the prognosis of these patients. We report our experience with 3 patients in whom a leukoreduction was performed in the context of severe pertussis and hyperleukocytosis.
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