出血性休克狗的左室功能变化

本文观察了出血性休克狗回输血液后的心功能变化。用4道生理记录仪记录血流动力学参数及左室内压(LVP)最大上升和下降速率(±dp/dt max),通过示波器同时摄取p-dp/dt环,并从环体测取dp/dt-DP5.33、心肌收缩成分缩短和延长速度(VCE和-VCE)、Vmax、-dp/dt max/LVSP。结果表明,当休克回输后10min血流动力学和心功能参数接近对照值。回输血60min可发生心功能降低,随即更趋恶化。结果提示:出血性休克狗回输血后的早期可出现严重心功能障碍。

Left Ventricular Function Change of Hemorrhagic Shock in the Dog

Left ventricular function change was investigated in dogs during the postin-fusion period of experimental hemorrhagic shock. Hemodynamic parameters and the first derivative of left ventricular pressure (dp/dt) were recorded with an 4-channal polygraph and LVP-dp/dt loop was displayed on an attached oscilloscope simultaneously. In the study, LV function was assessed by + dp/dtmax, dp/dt/DP5.33, VCE at +dp/dtmax, Vmax, - dp/dtmax, - dp/dtmax/LVSP and VCE at -dp/dtmax. The results show that hemodynamic and LV function parameters approximate to the control levels 10 min after reinfusion. The performance then depresses significantly 60 min after renfusion and cardiac function deteriorates soon thereafter. The data are interpreted as direct evidence for a seriously-depressing myocardial performance during the early postin-fusion period of hemorrhagic shock in the dog.