大黄附子汤在临床应用及药学分析

目的：分析讨论大黄附子汤在治疗慢性肾衰竭时的药学作用并评价疗效。方法：随机慢性肾衰竭患者（共60例）为对照组和观察组，各组均30例，均采用常规治疗，此外观察组额外使用大黄附子灌肠汤辅疗，经过3个疗程治疗后，通过对比两组患者血肌酐（SCr）、尿素氮（BUN）及总体有效率，计算肌酐清除率（Ccr），进而确定大黄附子汤是否具增效作用。结果：观察组与对照组相比，观察组SCr、BUN值明显低于对照组，Ccr值明显高于对照组，总体有效率也有明显提高。结论：治疗慢性肾衰竭患者时，大黄附子汤辅助治疗有良好的增效作用，可在临床治疗中推广使用。

Clinical application and pharmacy analysis of the rhubarb aconite decoction

Objective： To analysis the pharmacological action and efficacy of rhubarb aconite decoction in treating chronic renal failure. Method： 60 cases were divided into the observation group and control group, 30 for each. Both 2 groups were given the normal treatment. The observation group was given the rhubarb aconite decoction more. After 3 courses of treatment, by comparing the two groups of patients with serum creatinine （SCr）, urea nitrogen （BUN） and the total efficiency, calculated creatinine clearance rate （Ccr）, and then determine whether the rhubarb aconite decoction has synergism. Results： The observation group compared with control group, the SCr, BUN value is lower than the control group obviously, the Ccr values are significantly higher than the control group, the total efficiency have obviously improved. Conclusion： The Rhubarb and Aconite Decoction adjuvant therapy was effective in treating chronic renal failure, can be used widely in clinical treatment.