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Rapidly growing giant suprasellar tumor in a high-risk child: treatment strategy and role of neuroendoscopic surgery in slit-like ventricles
Authors:Saad Hamdan Abdullah  Koreaki Irie  Shizuo Oi
Institution:Division of Pediatric Neurosurgery, Women's and Children's Medical Center, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, 105-8461 Tokyo, Japan.
Abstract:RATIONALE: Suprasellar tumors are common in the pediatric population and exhibit a wide range of pathological appearance and behavior. Although rare, pure suprasellar germinomas carry worse prognosis than other locations. METHODS: We present a case of a 10-year-old girl treated with therapeutic anticoagulation for previous cardiac valvular replacement, who presented with rapidly growing giant (>4 cm) suprasellar germinoma. Neoadjuvant chemotheraphy was effective and the dilated ventricles became slit-like. The fine free-hand maneuver using a fine rigid-rod neuroendoscope. "Oi-Samii Handy Pro" made it possible to obtain the tissue diagnosis. RESULTS: Complete remission was achieved using neoadjuvant chemotherapy, minimally invasive neuroendoscopic surgery, then followed by specific chemoradiotherapy. CONCLUSION: The role of neuroendoscopic procedure, performed in a difficult situation with normalized size of the ventricles, was emphasized.
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