Lipoprotein profile of children with asthma receiving long-term theophylline therapy: a preliminary study. |
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| Authors: | P Yagupsky E Shahak A Tal J E Bearman I Zuili S Shany |
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| Institution: | Department of Pediatrics, Soroka Medical Center, Ben Gurion University of Negev, Beer-Sheva, Israel. |
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| Abstract: | Lipid profiles were determined in three groups of children: children with asthma receiving long-term therapy with slow-releasing theophylline, children with asthma not treated with theophylline, and a control group of children without asthma. Total cholesterol, high-density lipoprotein cholesterol, and apolipoprotein A levels and the high-density lipoprotein/low-density lipoprotein ratio were significantly higher among theophylline-treated children. The observed changes do not seem to increase the risks of atherosclerotic coronary artery disease. |
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