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奎硫平与氯氮平治疗精神分裂症的比较研究
引用本文:吴蒙.奎硫平与氯氮平治疗精神分裂症的比较研究[J].中国临床实用医学,2008,2(11):44-45.
作者姓名:吴蒙
作者单位:内蒙古精神卫生中心精神科,010010
摘    要:目的比较奎硫平和氯氮平治疗精神分裂症的临床疗效与安全性。方法对60例首次住院的精神分裂症患者,随机分为奎硫平和氯氮平两组,分别进行8周治疗,采用阳性症状与阴性症状量表(PANSS)及副反应量表(TESS)评定疗效及不良反应。结果两组疗效差异统计学意义(P〉0.05),奎硫平的不良反应少于氯氮平。结论奎硫平治疗精神分裂症疗效好,不良反应轻。

关 键 词:奎硫平  氯氮平  精神分裂症

A comparisons study on quetiapine and clozapine in the treatment of schizophrenic patients
WU Meng.A comparisons study on quetiapine and clozapine in the treatment of schizophrenic patients[J].China Clinical Practical Medicine,2008,2(11):44-45.
Authors:WU Meng
Institution:WU Meng (Inner Mongolia Mental Health Center, Huhhot 010010, China)
Abstract:Objective To compare the curative effectiveness and safety of adopting quetiapine and clozapine to treat schizophrenia.Methods 60 first episode admitted patients were randomly assigned to 8 weeks of treatment with either quetiapine and clozapine.was evaluated with PANSS and TESS.Results Effects of both drugs were similar in schizophrenic positive.There was no significant difference from their side effects rate (P>0.05).the side effects of quetiapine was less than that of clozapine.Conclusion The curative effectiveness of adopting quetiapine to treat schizophrenia is good,and its side effects are slight.
Keywords:Quetiapine  Clozapine  Schizophrenic
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