| 急性冠脉综合征患者血浆脑钠肽检测及其意义 |
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| 引用本文： | 王昌育,李涛,廖菽丹,辛渭川,丁辉,龚敏.急性冠脉综合征患者血浆脑钠肽检测及其意义[J].陕西医学杂志,2007,36(8):1001-1003. |
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| 作者姓名： | 王昌育 李涛 廖菽丹 辛渭川 丁辉 龚敏 |
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| 作者单位： | 西安市中心医院心内科,西安,710003 |
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| 摘 要： | 目的:探讨急性冠脉综合征(ACS)患者血浆脑钠肽(BNP)水平的变化及其临床意义。方法:85例ACS患者按临床类型分为:不稳定型心绞痛(UAP)组28例,急性非ST段抬高性心肌梗死(NSTEMI)组25例,急性ST段抬高性心肌梗死(STEMI)组32例,正常对照组25例,检测各组BNP浓度,通过超声心动图计算射血分数(EF)值和短轴缩短率(FS)值。结果:各组间BNP水平均有显著差异,各组间EF值相比无显著性差异。结论:BNP是反映ACS患者心肌缺血及损伤、坏死程度的敏感指标之一。
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| 关 键 词： | 冠状动脉疾病/诊断 利钠肽 脑/血液 对比研究 |
| 修稿时间： | 2007-03-05 |
The variation and significance of brain natriuretic peptide levels in patients with acute coronary syndrome |
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| Abstract: | Objective: To explore the variation and significance of brain natriuretic peptide (BNP) levels in patients with acute coronary syndrome (ACS) . Methods: 85 patients of ACS were enrolled in this study and 25 persons without CHD were selected as control. The patients of ACS included 28 UAP persons,25 NSTEMI persons and 32 STEMI persons. Plasma levels of BNP were detected by the method of ELISA: the values of EF were obtained by echocardiogram. Results: There was significance between the levels of BNP in different groups of ACS, and there was no significance between the values of EF and FS in different groups of ACS. Conclusion: Plasma level of BNP is a sensitive factor which indicates the degree of ischemia、damage and necrosis of myocardium in the patients of ACS |
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| Keywords: | Coronary disease/diagnosis Natriuretic peptide brain/blood Comparaive study |
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