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Hospital Frailty Risk Score Predicts Adverse Events in Primary Total Hip and Knee Arthroplasty
Institution:1. Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia;2. Department of Orthopaedics, Grady Memorial Hospital, Atlanta, Georgia;1. Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN;2. Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN;3. Department of Health Sciences and Research, Mayo Clinic, Rochester, MN;4. Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN;5. Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN;1. Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota;2. Department of Orthopedic Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota;3. Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, Rochester, Minnesota;4. Department of Health Services Research, Mayo Clinic College of Medicine, Rochester, Minnesota;1. Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia;2. Department of Orthopaedics, Emory University, Grady Memorial Hospital, Atlanta, Georgia
Abstract:BackgroundThe Hospital Frailty Risk Score (HFRS) is a validated geriatric comorbidity measure derived from routinely collected administrative data. The purpose of this study is to evaluate the utility of the HFRS as a predictor for postoperative adverse events after primary total hip (THA) and knee (TKA) arthroplasty.MethodsIn a retrospective analysis of 8250 patients who had undergone THA or TKA between 2011 and 2019, the HFRS was calculated for each patient. Reoperation rates, readmission rates, complication rates, and transfusion rates were compared between patients with low and intermediate or high frailty risk. Multivariate logistic regression models were used to assess the relationship between the HFRS and postoperative adverse events.ResultsPatients with intermediate or high frailty risk showed a higher rate of reoperation (10.6% vs 4.1%, P < .001), readmission (9.6% vs 4.3%, P < .001), surgical complications (9.1% vs 1.8%, P < .001), internal complications (7.3% vs 1.1%, P < .001), other complications (24.4% vs 2.0%, P < .001), Clavien-Dindo grade IV complications (4.1% vs 1.5%, P < .001), and transfusion (10.4% vs 1.3%, P < .001). Multivariate logistic regression analyses revealed a high HFRS as independent risk factor for reoperation (odds ratio OR] = 2.1; 95% confidence interval CI], 1.46-3.09; P < .001), readmission (OR = 1.78; 95% CI, 1.21-2.61; P = .003), internal complications (OR = 3.72; 95% CI, 2.28-6.08; P < .001), surgical complications (OR = 3.74; 95% CI, 2.41-5.82; P < .001), and other complications (OR = 9.00; 95% CI, 6.58-12.32; P < .001).ConclusionThe HFRS predicts adverse events after THA and TKA. As it derives from routinely collected data, the HFRS enables hospitals to identify at-risk patients without extra effort or expense.Level of EvidenceLevel III–retrospective cohort study.
Keywords:arthroplasty  outcome  complications  adverse events  HFRS  frailty
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