| Abstract: | Purpose] The aim of this study was to measure bone mineral density, serum and urinary
bone turnover parameters, and to evaluate the influence of demographic and genetic factors
on these parameters in FMF patients. Subjects and Methods] Twenty-seven attack-free
patients who were diagnosed with FMF (in accordance with Tel Hashomer criteria) were
recruited at outpatient rheumatology clinics. We investigated whether there were any
differences between the FMF patients and a control group in terms of lumbar and femur bone
mineral density (BMD), standard deviation scores (Z scores and T scores) and bone markers.
Results] In terms of the median values of lumbar BMD (p = 0.21), lumbar T (p = 0.098) and
Z (p = 0.109) scores, femoral neck BMD, femoral T and Z scores and total femur BMD, T (p =
0.788) and Z scores, there were no significant differences. Conclusion] In our study, no
statistically significant differences were found between FMF patients and a control group
in terms of osteoporosis. The 25-OH vitamin D was found to be significantly lower in FMF
patients than in the control group.Key words: Bone mineral density, Familial mediterranean fever, Serum bone markers levels |
