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Pathologic Versus Native Hip Fractures: Comparing 30-day Mortality and Short-term Complication Profiles
Institution:1. Department of Orthopaedic Surgery, Medical University Innsbruck, Innsbruck, Austria;2. Department of Orthopaedic Surgery-Experimental Orthopaedics, Medical University Innsbruck, Innsbruck, Austria;3. Department of Clinical Epidemiology of Tirol Kliniken GmbH, Innsbruck, Austria;1. Department of Orthopaedic Surgery, Inspira Health, Vineland, NJ;2. Department of Orthopaedic Surgery, The Rothman Institute, Egg Harbor Township, NJ;3. Advanced Orthopedics and Sports Medicine Institute, Freehold, NJ;4. Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA;1. Joint Replacement Center, Seoul Metropolitan SeoNam Hospital, Seoul, Republic of Korea;2. Department of Orthopedic Surgery, Ewha Womans University Seoul Hospital, Seoul, Republic of Korea;1. Department of Orthopaedic surgery and Traumatology, Charité University Hospital, Berlin, Germany;2. Walter Reed National Military Medical Center, Bethesda, MD;3. Department for Orthopaedics and Orthopaedic Surgery, University of Greifswald, Greifswald, Germany
Abstract:BackgroundA large body of research on native hip fractures has resulted in several evidence-based guidelines aimed at improving postsurgical care for these patients. In contrast, there is a paucity of data on pathologic hip fractures, and whether native hip fracture protocols are generalizable to this population is unknown. The purpose of this study was to compare mortality rates and complication profiles between patients with pathologic and native hip fractures.MethodsUsing the American College of Surgeons-National Surgical Quality Improvement Program (NSQIP) database, we identified patients who underwent surgical treatment for pathologic and native hip fractures from 2007 to 2017 and 2601 matched pairs were identified using propensity scoring. Baseline covariates were controlled for, and rates of 30-day postoperative complications and mortality were compared using McNemar’s test.ResultsPathologic hip fracture patients experienced significantly higher rates of death (6.3% vs 4.3%, P < .001), serious adverse events (17.3% vs 13.5%, P < .001), minor complications (34.3% vs 29.1%, P < .001), extended postoperative lengths of stay (30.2% vs 25.9%, P < .001), readmissions (11.9% vs 8.4%, P < .001), thromboembolic complications (3.0% vs 1.6%, P < .001), and perioperative transfusions (31.5% vs 26.4%, P < .001) compared to native hip fracture patients.ConclusionPathologic hip fractures result in significantly higher complication rates than native hip fractures after surgical treatment, suggesting that guidelines for native hip fractures may not be generalizable for pathologic hip fractures. Orthopedic surgeons should closely monitor these patients for deep vein thrombosis, utilize blood sparing techniques, and employ a multidisciplinary approach to help manage and prevent a more heterogenous profile of postsurgical complications.
Keywords:pathologic fracture  proximal femur  hip  complications  mortality  morbidity
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