Congenital Cytomegalovirus and Hearing Loss |
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| Institution: | 1. Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan;2. Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan;3. Department of Obstetrics and Gynecology, Hyogo Prefectural Kobe Children''s Hospital, Kobe, Japan;4. Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan;1. Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia;2. Center for Proteomics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia;3. Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA;4. Department of Pediatrics Infectious Disease, University of Alabama at Birmingham, Birmingham, AL, USA;1. Division of Infectious Diseases and Immunology, Saitama Children''s Medical Center, Saitama, Japan;2. Division of Otorhinolaryngology, Kawagoe Otology Institute, Saitama, Japan;3. Division of Otolaryngology, Saitama Children''s Medical Center, Saitama, Japan;4. Department of Pharmacy, Saitama Children''s Medical Center, Saitama, Japan;5. MicroSKY Lab, Inc., Tokyo, Japan;6. The Medical and Nursing Institution of Akitsu Ryoiku-En for Children/Adults with Severe Motor and Intellectual Disabilities, Tokyo, Japan |
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| Abstract: | Congenital cytomegalovirus (cCMV) is the most common cause of nongenetic, sensorineural hearing loss and neurodevelopmental disorders in newborns, infants, and children. Current cCMV screening procedures for pregnant women and newborns are not standardized, which may be attributed to the lack of knowledge about the consequences of infection among clinicians and the general public and the lack of effective treatments. The purpose of this article is to provide a review and update on cCMV infection epidemiology, diagnostic tests, clinical manifestations, prevention, treatment, and nursing implications. Hearing loss is emphasized because this is a common sequela of cCMV infection for which diagnostic modalities and treatments are available. |
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| Keywords: | congenital abnormalities congenital cytomegalovirus infection congenital infection cytomegalovirus vaccine health education sensorineural hearing loss |
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