| Histopathological and molecular prognostic markers in medulloblastoma： c-myc, N-myc, TrkC, and anaplasia |
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| 作者姓名： | EberhartCG KratzJ WangY SummersK StearnsD CohenK DangCV BurgerPC |
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| 作者单位： | DepartmentofPathology,JohnsHopkinsUniversitySchoolofMedicine,Baltimore,Maryland21287,USA |
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| 摘 要： | Several molecular and histopathologieal prognostic markers have been proposed for the therapeutic stratification of meduUoblastoma patients. Amplification of the c-mye oneogene, elevated levels of c-mye mRNA, or tumor anaplasia have been associated with worse clinical outcomes. In contrast, high TrkC mRNA expression generally presages longer survival. The goal of this study was to evaluate the
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| 关 键 词： | c-myc RNA N-myc |
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