586例胃癌的临床分析

目的：研究讨论年龄、性别因素与胃癌的发病和临床病理学之间的关系。方法：收集1998年1月至2008年1月在本院接受外科手术治疗的586例胃癌患者的手术后病理学资料，比较分析不同胃癌患者的性别、年龄分布情况及临床病理学差异。结果：胃癌的发病率随着年龄的增长而升高，51-60岁为高峰年龄段，40岁以下女性发病多于男性，40岁以上则相反。40岁以下胃癌患者的组织学类型大多为分化较差的低分化腺癌或者印戒细胞癌（63％-89％），40岁以上的患者中分化腺癌的比例逐渐增高，男性尤其明显；低分化腺癌和印戒细胞癌是各年龄段女性胃癌的主要组织学类型。结论：不同性别、年龄组胃癌患者具有不同的发病状况和组织学类型。

CLINICAL ANALYSIS OF 586 CASES OF GASTRIC CANCER

Objective： To investigate the effect of gender and age on morbidity and clinicopathology of gastric carcinoma. Methods： Formalin-fixed, paraffin-embedded human gastric carcinoma specimens were obtained from the Pathology Department of the people＇s hospital of JiangYou between 1998 and 2008. The morbidity and clinicopathologieal features were compared and analyzed to explore the effect of gender and age of the patients on morbidity and clinicopathological features. Result： The incidence of gastic cance increased along with the age in both genders and reached a high plateau in 51-60 year group. Female patients predominated at the age of 40 years age or younger, and male patients predominated at the cases elder than 40 years. Poorly differentiated cancer possessed with 63%-89% in male and female patients at the age of 40 years or younger. The incidence of middle-differentiated adenocarcinoma increased along with the age of patients elder than 40 years especially in males, low-differentiated adenocarcinoma and signet ring cancer were the main types of the tumor in various aged females. Conclusion： Different gender and age of the patients with gastric cancer present different incidence and elinicopathological features.