Progression and extending speed of Barrett's esophagus

Barrett's esophagus is one of the terminal manifestations of reflux esophagitis. Although the typical Barrett's esophagus is very rare in Japan, the prevalence rate of short-segment Barrett's esophagus is extremely higher comparing with in western countries. The discrepancy may be caused by the differences of criteria of short-segment Barrett's esophagus. Observation of Barrett's mucosa in residual esophagus after esophagectomy is a useful method of considering the extension of Barrett's esophagus. Short-segment Barrett's esophagus accompanied by gastro-esophageal reflux may show a rapid extension under some adequate conditions. Large volume prospective studies are needed to clarify the extension speed of Barrett's esophagus.