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血脂康对原发性高脂血症的疗效及随访观察
引用本文:石湘芸,朱智明.血脂康对原发性高脂血症的疗效及随访观察[J].天津医药,1997,25(12):710-713.
作者姓名:石湘芸  朱智明
作者单位:中国人民解放军海军总医院心内科,中国人民解放军海军总医院心内科,中国人民解放军海军总医院心内科,中国人民解放军海军总医院心内科,中国人民解放军海军总医院心内科,中国人民解放军海军总医院心内科,中国人民解放军海军总医院心内科 100037 北京,100037 北京,100037 北京,100037 北京,100037 北京,100037 北京,100037 北京
摘    要:用血脂康胶囊治疗60例原发性高脂血症患者。经8周临床观察,结果示降总胆固醇(TC)、甘油三酯(TG),长高密度脂蛋白胆固醇(HDL-C),降(TC-HDL-C)/HDL-C的总有效率分别占95.5%、82.5%、85.4%和88.3%;平均降TC、TG、LDC-C、(TC-HDL-C)/HDL-C、升HDL-C分别为25%、35.6%、28.6%、31.2%和22.6%。各组与治疗前比较有非常显著

关 键 词:高脂血症  血脂康  疗效  药物疗法

Clinical Evaluation and Follow-up Study of Xuezhikang Treatment of Primary Hyperlipidemia
Shi Xiangyun,Zhu Zhiming,Tian Huisheng,et al.Clinical Evaluation and Follow-up Study of Xuezhikang Treatment of Primary Hyperlipidemia[J].Tianjin Medical Journal,1997,25(12):710-713.
Authors:Shi Xiangyun  Zhu Zhiming  Tian Huisheng  
Institution:Shi Xiangyun,Zhu Zhiming,Tian Huisheng,et al Department of Cardiology,Naval General Hospital,Beijing 100037
Abstract:Sixty patients with hyperlipidemia were treated with Xuezhikorig (a lipid-lowering drug) for 8 weeks,each took 4 Xuezhikong capsules/day. The results showed that serum levels of total cholesterol (TC),triglyceride(TG),low density lipoprotein cnolesterol(LDL-C) and the ratio of (TC -HDL-C)/ HDL-C were reduced by 25% ,35. 6% ,28. 6% and 31. 2% respectively,and serum level of high density lipoprotein cholesterol (HDL-C) was increased by 22. 6%- The total effectiveness rates of Xuezhikang for TC,TG,HPL-C and (TC-HDL-C)/HDL-C were 95. 5% ,82. 5% ,85. 4% and 88. 3% respectively. The serum levels of TC,TG,LDL-C and the ratio of (TC - HDL-C)/HDL-C were significantly lower after treatment than those before treatment (all P<0. 01) and the serum level of HDL-C was significantly higher after treatment than that before treatment (P<0. 01). The results showed that Xuezhikang is a safe and effective lipid modulator. All Patients had been followed up for 8 weeks,the serum levels of lipids were normal in those patients who continued to take 2 Xuezhikang capsules/day for another 8 weeks, but the serum levels of lipids reversed in those who didn't continue to take Xuezhikang. We suggest that all patients with improvement had better take half-dose Xuezhikang continuously to avoid rebounding of hyperlipidemia.
Keywords:Xuezhikang hyperlipidemia efficacy follow up
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