新诊断多发性骨髓瘤诊治进展：2014年国际骨髓瘤工作组高峰论坛报道

2014国际骨髓瘤工作组（IMWG）高峰论坛重点讨论了多发性骨髓瘤（MM）的诊断标准,提出了无症状性骨髓瘤（aMM）危险分层标准及随访和治疗观点.重点讨论了治疗方案的选择及新药时代美法仑的地位、老年MM患者治疗方案的选择;对于巩固及维持治疗,由于出现各种不同的研究结果,对其地位及治疗的人群选择提出了讨论.尽管可以对MM进行危险分层,但对确切的分层指标仍存在争议,仍应以规范治疗为宜.

Diagnosis and treatment of newly diagnosed multiple myeloma: the focus of 2014 International Myeloma Working Group summit

2014 International Myeloma Working Group （IMWG） summit was held in Milan at June 2014. During this meeting, the criteria of asymptomatic and symptomatic multiple myeloma was revised. No benefit was shown with conventional treatment for asymptomatic patients. Frontline therapy in newly diagnosed multiple myeloma, also in elderly patients was discussed. Individualized treatment, especially for genetic risk stratification should be done, but randomized control studies needed to be done to confirm its feasibility.