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原发性肝癌治疗前后血清可溶性上皮钙粘蛋白水平变化的研究
引用本文:邓晓军,李立志,李振洪,黄华艺,葛益谋. 原发性肝癌治疗前后血清可溶性上皮钙粘蛋白水平变化的研究[J]. 华夏医学, 2001, 14(4): 417-418
作者姓名:邓晓军  李立志  李振洪  黄华艺  葛益谋
作者单位:1. 广西民族医院肝胆外科,
2. 广西民族医院检验科
摘    要:目的:探讨原发性肝癌(HCC)患者治疗前,后的血清可溶性上皮钙粘蛋白(SE-Cadherin)水平变化,方法:用酶联免疫吸附双抗体夹心法检测26例HCC患者治疗前,后的血清SE-Cadherin水平及21例正常健康人血清SE-Cadherin水平。结果:原发性肝癌患者治疗前血清SE-Cadherin水平明显高于治疗后,其差异有显著性意义(P<0.01),而正常健康人血清SE-Cadherin水平不高,结论:血清SE-Cadherin 水平的测定可作为原发性肝癌的诊断及疗效观察指标,并有可能成为预后评判和复发指标。

关 键 词:原发性肝癌 可溶性上皮钙粘蛋白 ELISA法 HCC 诊断 预后
文章编号:1008-2409(2001)04-0417-02
修稿时间:2001-03-26

The Changes of Serum SE-Cadherin Levels Before and After Treatment in Cases of Hepatocarcinoma
DENG Xiao jun,LI Li zhi,LI Zheng hong,et al.. The Changes of Serum SE-Cadherin Levels Before and After Treatment in Cases of Hepatocarcinoma[J]. Acta Medicinae Sinica, 2001, 14(4): 417-418
Authors:DENG Xiao jun  LI Li zhi  LI Zheng hong  et al.
Affiliation:DENG Xiao jun,LI Li zhi,LI Zheng hong,et al.//Department of Surgery,Guanxi National Hospital,Nanning 530001
Abstract:Objective:To study the changes of serum SE Cadherin levels before and after treatment in patients with hepatocarcinoma.Methods:The serum SE Cadherin levels were measured in 26 patients with hepatocarcinoma and 21 normal subjects by the enzyme immunosorbent double antibody technique.Results:Before the treatment,the patients with hepatocarcinoma showed a higher serum SE cadherin level as compared to that after the treatment( P <0.01).The serum SE Cadherin level in control group was not high.Conclusion:The serum SE Cadherin level may be an indicator for diagnosis of, and treatment effect in hepatocarcinoma
Keywords:hepatocarcinoma  serum SE Cadherin
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