小承气汤加味联合熊去氧胆酸治疗脂肪肝的效果

目的观察小承气汤加味联合熊去氧胆酸治疗脂肪肝的临床效果。方法选择我院门诊或住院的脂肪肝病人120例，随机分为2组。在一般治疗的基础上，治疗组应用小承气汤加味联合熊去氧胆酸治疗，对照组应用凯西莱和脂必妥治疗。比较两组治疗前后临床症状和体征、血脂、肝功能及肝脏B超影像学的变化。结果治疗组总有效率为95％，疗效明显优于对照组（u=3．16，P〈0．05）。小承气汤加味联合熊去氧胆酸能显著改善病人的脂肪肝B超影像，缓解临床症状，改善肝功能，降低血三酰甘油、胆固醇含量。结论小承气汤加味联合熊去氧胆酸是治疗脂肪肝的有效方法。

EFFICACY OF ADDITIONAL XIAOCHAIHU DECOCTION COMBINED WITH URSODEOXYCHOLIC ACID FOR FATTY LIVER

Objective To assess the therapeutic effect of Xiaoehaihu decoction combined with ursodeoxycholie acid for patients with fatty liver. Methods This study consisted of 120 patients with fatty liver, who were randomized to combotherapy group and control group. Beside general therapy, Xiaoehaihu decoction plus ursodeoxycholie acid was offered to combotherapy group; Tiopronin and Zhibituo to the control. The symptoms, signs, liver function, and sonographic findings, before and after treatment, were compared between the two groups. Results The total effective power was 95% for combotherapy, being superior to the control （u=3.16, P〈0.05）. Xiaochaihu decoction plus ursodeoxycholic acid significantly improved the patients＇ sonographic image, blood lipid, and symptoms. Conclusion The combination medication of Xiaoehaihu decoction and ursodeoxycholic acid is an effective therapeutics for fatty liver.