俯卧位通气法对急性呼吸衰竭病人氧合状态的影响

目的探讨俯卧位通气法对急性呼吸衰竭病人氧合状态的影响。方法对46例急性呼吸衰竭病人共进行了60次俯卧位机械通气治疗,监测仰卧位、俯卧位1、2h的呼吸循环指标,并进行比较。结果俯卧位1、2h后病人动脉血氧分压、氧合指数较仰卧位时明显升高（t=4.042～7.923,P〈0.01）,心率、平均动脉压、气道阻力、肺顺应性和动脉血二氧化碳分压与仰卧位比较差异无显著性（P〉0.05）,以氧分压增加幅度大于1.33kPa为有效标准,俯卧位通气法治疗有效率达86.7%。结论俯卧位通气法能明显改善急性呼吸衰竭病人的氧合状况。

EFFECT OF PRONE POSITION VENTILATION ON OXYGENATION SITUATION IN PATIENTS WITH ACUTE RESPIRATORY FAILURE

Objective To investigate the effect of prone position ventilation on oxygenation situation in patients with acute respiratory failure （ARF）. Methods Forty-six ARF patients were ventilated on prone position for 60 times. One-hour and two-hour respiratory-circulatory indices of supine and prone-position were monitored. Results PaO2 and oxygenation index significantly increased on prone position compared with that of supine position （t=4. 042-7. 923 ,P〈0.01）. No statistical differences were found in HR, MAP, PaCO2, airway resistance and compliance of lungs between the two positions （P〉0. 05）. If 1.33 kPa increase in PaO2 was regarded as the standard parameter of treatment effectiveness, the effective rate in the prone position ventilation was 86.7%. Conclusion Prone position ventilation can significantly improve the oxygenation situation of patients with ARF.