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复方血竭制剂与5-氨基水杨酸在溃疡性结肠炎临床维持缓解治疗中的疗效比较
引用本文:吴凯,李楠,张林,王雪明,王欣,翟俊山,王艳梅,石玉玲. 复方血竭制剂与5-氨基水杨酸在溃疡性结肠炎临床维持缓解治疗中的疗效比较[J]. 临床军医杂志, 2008, 36(4)
作者姓名:吴凯  李楠  张林  王雪明  王欣  翟俊山  王艳梅  石玉玲
作者单位:解放军总医院附属第二医院,消化科,北京,100091;解放军总医院附属第二医院,消化科,北京,100091;解放军总医院附属第二医院,消化科,北京,100091;解放军总医院附属第二医院,消化科,北京,100091;解放军总医院附属第二医院,消化科,北京,100091;解放军总医院附属第二医院,消化科,北京,100091;解放军总医院附属第二医院,消化科,北京,100091;解放军总医院附属第二医院,消化科,北京,100091
摘    要:目的比较复方血竭灌肠液及口服5-氨基水杨酸(SASP)在溃疡性结肠炎(UC)临床维持缓解治疗中的疗效。方法以血竭、白芨为原料制备复方血竭灌肠液,对51例UC患者(血竭组)进行灌肠治疗6个月;SASP组给予SASP1.5g1次/d口服维持6个月,比较两组患者的复发率及治疗中的副作用。结果血竭组和SASP组疗效间差别无显著性意义(P>0.05);血竭组消化道反应、血液系统毒性、肝肾功能损害明显小于对照组(P<0.01)。结论复方血竭灌肠可用于高危患者及SASP治疗无效者的维持治疗方案。

关 键 词:复方血竭制剂  溃疡性结肠炎  柳氮磺胺吡啶  维持缓解

Evaluation on Compound Dracorhodin Enema and Sulfasalazine in Maintenance Treatment for Clinical Remission of Ulcerative Colitis
Wu Kai,Li Nan,Zhang Lin,Wang Xue-ming,Wang Xin,Zhai Jun-shan,Wang Yan-mei,Shi Yu-ling. Evaluation on Compound Dracorhodin Enema and Sulfasalazine in Maintenance Treatment for Clinical Remission of Ulcerative Colitis[J]. Clinical Journal of Medical Officer, 2008, 36(4)
Authors:Wu Kai  Li Nan  Zhang Lin  Wang Xue-ming  Wang Xin  Zhai Jun-shan  Wang Yan-mei  Shi Yu-ling
Affiliation:Wu Kai,Li Nan,Zhang Lin,Wang Xue-ming,Wang Xin,Zhai Jun-shan,Wang Yan-mei,Shi Yu-ling (Department of Digestive Medicine,Second Affiliated Hospital of PLA General Hospital,Beijing 100091,China)
Abstract:Objective To compare the clinical efficacy of liquid compound dracorhodin enema and sulfasalazine in the maintenance treatment for remission of ulcerative colitis (UC). Methods Dracorhodin and bletilla striata were compounded into enema for the preparation of treatment, which was then administered to 51 patients of UC (dracorhodin group) for six months. Oral sulfasalazine (1.5 g per day) were meanwhile given to another group of patients (control group). The curative effects were evaluated by comparing the r...
Keywords:compound dracorhodin enema  ulcerative colitis  sulfasalazine  maintenance treatment  
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