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伊贝沙坦影响原发性高血压病人左心室肥厚的临床研究
引用本文:周昭烈,何旭亮,陈平. 伊贝沙坦影响原发性高血压病人左心室肥厚的临床研究[J]. 中国现代医学杂志, 2003, 13(13): 78-79
作者姓名:周昭烈  何旭亮  陈平
作者单位:1. 广东省潮阳市第二人民医院,515144
2. 汕头市中心医院
摘    要:目的 :研究伊贝沙坦 (Irbesartan)对原发性高血压病人左心室肥厚 (LVH)的影响。方法 :将 6 0例高血压病左心室肥厚的病人随机分为伊贝沙坦组 (2 5例 )和依那普利组 (35例 ) ,疗程半年。分别于治疗前后测量血压、作超声心动图 (UCG)检查测量指标计算左心室质量指数。结果 :两组治疗后血压、左心室质量指数均比治疗前显著下降 (P <0 .0 1) ,但组间无显著差异 (P >0 .0 5 )。结论 :伊贝沙坦能有效降低高血压病左心室肥厚病人的血压 ,逆转LVH。

关 键 词:伊贝沙坦 依那普利 原发性高血压 左心室肥厚
修稿时间:2003-03-11

EFFECT OF IRBESATA ON THE LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH ESSENTIAL HYPERTENSION
Zhou Zhaolie,He Xuliang,Chen Ping The Second People's Hospital of Chaoyang City,Guangdong Province. EFFECT OF IRBESATA ON THE LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH ESSENTIAL HYPERTENSION[J]. China Journal of Modern Medicine, 2003, 13(13): 78-79
Authors:Zhou Zhaolie  He Xuliang  Chen Ping The Second People's Hospital of Chaoyang City  Guangdong Province
Affiliation:Zhou Zhaolie,He Xuliang,Chen Ping The Second People's Hospital of Chaoyang City,Guangdong Province,515144
Abstract:Objective:To explore the effect of Irbesartan on the left ventricular hypertrophy(LVH) in patients with essential hypertension. Methods: 60 patients with essential hypertension who had LVH were divided into two groups randomly. One was Irbesartan geoup(25 cases)and the other was Enalapril group(35 cases).Half-a-year therapy. We measured the blood pressure and examined UCG to get the details to measure the left ventricular mass index (LVMI) before and after thearapy.Results:The blood pressure and LVMI after therapy of two groupsboth decreased markedly than those before therapy with no significant difference between them.Conclusions:Irbesartan can reduce the blood pressure effectivelyand rever LVH in patient with essential hypertension who have LVH.
Keywords:Irbesartan  Enalapril  Essential Hypertension  Left Ventricular Hypertension (LVH)
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