Chloroquine resistant Plasmodium falciparum on the island of Flores, Indonesia |
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| Authors: | L L Smrkovski,S L Hoffman,R P Purnomo Y" >Hussein,S Masbar,L Kurniawan |
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| Affiliation: | 1. U.S. Naval Medical Research Unit No. 2, Manila, Philippines;2. U.S. Naval Medical Research Unit No. 2, Jakarta, Indonesia;3. Health Service, Kabupaten Manggarai, Flores, Nusa Tenggara Timur, Indonesia;4. Immunology Division, and Institute for Health Research and Development Ministry of Health, Jakarta, Indonesia |
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| Abstract: | The in vitro sensitivity of Plasmodium falciparum to chloroquine was studied in parasites from 45 children on the island of Flores, Indonesia. The micro in vitro culture technique and a 12-volt battery-operated field incubator were found to be well suited to the field situation encountered. Parasites from seven children (15.6%) were resistant to chloroquine in vitro: two at 8 pico-moles of chloroquine, two at 16 pico-moles, and three at 32 pico-moles. This is the first report of chloroquine resistant from Flores. |
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