| 西拉普利和牛磺酸对慢性缺氧肺组织细胞凋亡的影响 |
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| 引用本文： | 黄文杰,邹霞英,姜辉. 西拉普利和牛磺酸对慢性缺氧肺组织细胞凋亡的影响[J]. 中国病理生理杂志, 1999, 15(7): 663-665 |
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| 作者姓名： | 黄文杰 邹霞英 姜辉 |
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| 作者单位： | 广州军区广州总医院呼吸内科,510010,广州 |
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| 摘 要： | 目的：初步观察西拉普利和牛磺酸对慢性缺氧肺组织细胞凋亡的影响。方法：采用原位末端民法。结果：缺氧模型及普利组细胞凋亡明显高于其他各组，而牛磺酸组、自然恢复组册与正常对照无差异。结论：西拉普利可能诱发细胞凋亡的作用，细胞凋亡的发生与否可能与肺动脉高压的形成与发展有关。
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| 关 键 词： | 牛磺酸 缺氧 肺动脉高压 细胞凋亡 西拉普利 |
Influence of cilazapril and taurine on apoptosis of chronic hypoxic lung tissue |
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| HUANG Wen-Jie,ZOU Xia-Ying,JIANG Hui. Influence of cilazapril and taurine on apoptosis of chronic hypoxic lung tissue[J]. Chinese Journal of Pathophysiology, 1999, 15(7): 663-665 |
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| Authors: | HUANG Wen-Jie ZOU Xia-Ying JIANG Hui |
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| Abstract: | AIM: The influence of cilazapril and taurine on apoptosis of chronic hypoxic lung tissues was observed. METHOD:The in situ end-labelling procedure was used. RESULTS:The number of all apoptosis in hypoxic model and Cilazapril groups was much greater than those of other groups( P <0.01). There was no difference between the natural recovery group and normal controls. CONCLUSION:Cilazapril might induce apoptosis, and apoptosis might be related to the formation and development of pulmonary hypertension. |
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| Keywords: | Taurine Cell hypoxia Lung |
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