丹参多酚酸盐联合尿激酶治疗STEMI后心绞痛的疗效分析

目的：观察丹参多酚酸盐联合尿激酶治疗急性S T段抬高型心肌梗死后心绞痛的疗效及安全性。方法将124例患者分成治疗组和对照组，每组62例。两组均给予冠心病二级预防治疗及溶栓治疗（尿激酶150万U溶于生理盐水100 m L中30 min内滴完），随后对照组给予极化液治疗，治疗组给予丹参多酚酸盐200 mg稀释于5％葡萄糖或生理盐水250 mL中静脉滴注15 d。观察两组心肌梗死后心绞痛发生情况、疗效及安全性。结果治疗组心绞痛发生率为25．81％，对照组心绞痛发生率为56．45％，两组比较差异有统计学意义（ P＜0．05）。结论应用丹参多酚酸盐联合尿激酶治疗急性S T段抬高型心肌梗死，可以显著减少心肌梗死后心绞痛，临床疗效好，不良反应少，安全性好。

Curative effect analysis of salvia miltiorrhiza salt in the treatment of angina pectoris after thrombolysis of acute ST-elevation myocardial infarction

Objective To compare the curative effect and safety of salvia miltiorrhiza salt combined with urokinase and sim‐ple application of urokinase in the treatment of angina pectoris after thrombolysis of acute ST‐elevation myocardial infarction .Meth‐ods Totally 124 cases patients were random divided into treatment group and control group ,62 cases in each group ,two group were given coronary heart disease Ⅱ level prevention treatment and dissolved tied treatment (urine kinase 1 .5 million U dissolved Yu saline 100 mL in the 30 minutes within drops finished ,only with a times) ,then control group was given polarization liquid treat‐ment ,treatment group was given Salvia more phenol acid salt 200 mg diluted Yu 5% glucose or saline 250 mL in the vein drops note 15 days ,incidence of myocardial infarction and angina pectoris and drug side effects were observed .Results Incidence of angina pectoris was 25 .81% in the treatment group and control group was 56 .45% ,there were significant differences in the two groups (P<0 .05) .Conclusion Application of phenolic acids from salvia miltiorrhiza salt combined with urokinase in the treatment of a‐cute ST‐elevation myocardial infarction ,myocardial infarction and angina pectoris can be significantly reduced ,and with good clinical efficacy and fewer side effects ,and it is safety .