犬牙移入牵张成骨区龈沟液 AST 水平动态变化

目的：研究分析不同时机将犬牙移入牵张成骨区后龈沟液的天门冬氨酸氨基转移酶（AST ）水平变化。方法8只无牙周疾病且正常恒牙列beag le犬行牵张成骨术后分为两组（2周和6周），均行牙齿移入牵张成骨新骨区。观察对实验牙加力1、2、3、7、14、28 d后龈沟液中AST水平变化。结果两组实验牙龈沟液AST水平前3 d均存在上升趋势，且2周组上升较6周组明显；7 d后AST水平呈现下降趋势，在21 d达最低，并逐渐恢复；当28 d时AST水平再次上升。结论牵张成骨2周后实验牙移入新骨区龈沟液AST整体水平较6周后明显升高，但随着时间的推移AST水平改变并非呈线性升高。

Dynamic changes of aspartate transaminase level in gingival crevicular fluid on tooth movement in new bone area

Objective To observe the dynamic changes of aspartate transaminase(AST ) in gingival crevicular fluid on tooth movement in new bone area after distraction osteogenesis at different time .Methods The distraction osteogenesis surgical proce‐dure was performed in 8 beagle dogs without periodontal disease and normal teeth ,experimental teeth were transplanted into the bone regeneration area after 2 weeks and after 6 weeks .Comparative analysis AST of each time (1 ,2 ,3 ,7 ,14 ,28 d after distraction) dynamic changes in gingival crevicular fluid .Results The AST level of gingival crevicular fluid in experimental tooth was rising for the first three days ,and the group of two weeks were significantly higher than 6 weeks ;AST levels after 7 d showed a trend of de‐cline ,down to the lowest point at 21 d ,and gradually restored ,AST levels reached a higher level again in the 28 d .Conclusion The AST level of experimental teeth increased significantly after 2 weeks than after 6 weeks ,but over time the AST level change is not linear ,this change has certain guiding significance for the clinical research in the future .