| 富硒超氧化物歧化酶绿茶对糖尿病大鼠降糖效应的研究 |
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| 引用本文： | 张萌,蒋宝泉,孙海岚,陈巧,林欣,王雪娇,宋晓瑜.富硒超氧化物歧化酶绿茶对糖尿病大鼠降糖效应的研究[J].肠外与肠内营养,2009,16(2). |
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| 作者姓名： | 张萌 蒋宝泉 孙海岚 陈巧 林欣 王雪娇 宋晓瑜 |
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| 作者单位： | 1. 第三军医大学大坪医院野战外科研究所营养科,重庆,400042
2. 装甲兵技术学院门诊部,吉林长春,130117 |
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| 摘 要： | 目的:观察富硒超氧化物歧化酶(SOD)绿茶对糖尿病大鼠的降糖效应.方法:30只四氧嘧啶制作成功的Wistar糖尿病模型大鼠,随机分为糖尿病对照组(B组)、普通绿茶组(C组)和富硒SOD绿茶组(D组),另取10只大鼠为正常对照组(A组).在常规饲料自由进食饮水的基础上,A组和B组给予蒸馏水灌胃,C组和D组分别给予普通绿茶粉溶液和富硒SOD绿茶粉溶液灌胃.测定大鼠空腹血糖(FPG)、糖耐量(OGTT)、糖化血清蛋白(GSP)、丙二醛(MDA)含量和超氧化物歧化酶(SOD)活力.结果:D组大鼠分组喂养后30、60和90 d FPG和0.5、1.0、1.5、2.0 h的OGTT测定值均显著或非常显著低于C组和B组(P<0.05,P<0.01);而C组分组喂养后60和90 d后,FPG和1.5、2 h的OGTT测定值显著或非常显著低于B组(P<0.05,P<0.01);C组GSP含量显著低于B组,D组显著或非常显著低于C组和B组;C组血清SOD活性显著高于B组,D组血清SOD活力和MDA含量与B组、C组均存在显著或非常显著性差异.结论:普通绿茶和富硒SOD绿茶均具有降血糖效应,但富硒SOD绿茶效果更好,其降糖效应可能与其改善糖尿病大鼠机体抗氧化能力有关.
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| 关 键 词： | 糖尿病 大鼠 硒 超氧化物歧化酶 绿茶 |
Hypoglycemic effect of selenium-enriched compound SOD green tea in diabetic rats |
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| ZHANG Meng,JIANG Bao-quan,SUN Hai-lan,CHEN Qiao,LIN Xin,WANG Xue-jiao,SONG Xiao-yu.Hypoglycemic effect of selenium-enriched compound SOD green tea in diabetic rats[J].Parenteral & Enteral Nutrition,2009,16(2). |
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| Authors: | ZHANG Meng JIANG Bao-quan SUN Hai-lan CHEN Qiao LIN Xin WANG Xue-jiao SONG Xiao-yu |
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| Institution: | 1.Department of Clinical Nutrition;Daping Hospital;the Third Military Medical University;Chongqing 400042;China;2.Clinic department of the Armored Technique Instituition;Changchun 130117;Jilin;China |
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| Abstract: | Objective:To study the hypoglycemic effect of selenium-enriched compound SOD green tea in diabetic rats.Methods:30 adult Wister rats induced diabetic models by alloxan were randomly divided into DM group(B),green tea group(C)and selenium-enriched compound SOD green tea group(D),and another 10 normal rats were attributed to control group(A).A and B were treated with intragastric administration of distilled water,while green tea and selenium-enriched compound SOD green tea were administrated for C and D respe... |
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| Keywords: | Diabetes mellitus Rats Selenium SOD Green tea |
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