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帕瑞昔布对腹腔镜胆囊切除术患者术后镇痛及血小板聚集的影响
引用本文:金鑫,嵇富海,杨建平.帕瑞昔布对腹腔镜胆囊切除术患者术后镇痛及血小板聚集的影响[J].江苏医药,2011,37(2).
作者姓名:金鑫  嵇富海  杨建平
作者单位:苏州大学附属第一医院麻醉科,215006
摘    要:目的探讨帕瑞昔布对患者术后镇痛及血小板聚集的影响。方法腹腔镜胆囊切除术患者30例,随机均分成2组,采用全凭静脉麻醉,术毕静注帕瑞昔布0.8mg/kg(P组)或生理盐水10ml(C组)。术前和术后30min抽取患者静脉血测定血小板聚集;记录术后安静时和活动后VAS评分。结果 P组在术后12、24h的安静时VAS评分和术后12h的活动后VAS评分均低于C组(P<0.05)。P组术前和术后血小板聚集情况差异无统计学意义(P>0.05)。结论帕瑞昔布0.8mg/kg对腹腔镜胆囊切除术患者具有显著的术后镇痛效果,但对血小板聚集无显著影响。

关 键 词:帕瑞昔布  血小板聚集  

Analgesic effect of parecoxib for patients undergoing laparoscopic cholecystectomy and its influence on platelet aggregation
JIN Xin,JI Fuhai,YANG Jianping.Analgesic effect of parecoxib for patients undergoing laparoscopic cholecystectomy and its influence on platelet aggregation[J].Jiangsu Medical Journal,2011,37(2).
Authors:JIN Xin  JI Fuhai  YANG Jianping
Institution:JIN Xin,JI Fuhai,YANG Jianping.Department of Anesthesiology,First Affiliated Hospital,Soochow University,Suzhou 215006,CHINA
Abstract:Objective To evaluate the analgesic effect of parecoxib for patients undergoing laparoscopic cholecystectomy and its influence on platelet aggregation.Methods Thirty patients undergoing laparoscopic cholecystectomy and total intravenous anesthesia were randomly assigned into two groups with 15 cases each.At the end of operation,the patients in group P were intravenously administered parecoxib 0.8 mg/kg and those in group C normal saline 10 ml as the controls.VAS scores at rest and after movement were record...
Keywords:Parecoxib  Platelet aggregation  
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