慢性活动性肝炎治疗探讨

本文总结了我科自1982～1988年共收治的101例慢性肝炎治疗的疗效观察,其中慢活肝53例,临床治愈86.7％,好转13.3％,无1例死亡,有效率100％;慢重肝48例,临床治愈31.2％,好转14.5％,无效26例,有效率45.8％。本组资料提示,慢活肝应用任何药物组合治疗,疗效都较好;慢重肝对各组治疗方法的疗效,与病情严重程度、有无并发症和MOSF有关。目前慢重肝病死率仍在50％以上,我们认为,在综合性治疗上加用FLC输注,可提高其存活率。此外,防治并发症与MOSF的发生也不可忽视。这常是治疗成败的关键。

TREATMENT OF CHRONIC ACTIVE HEPATITIS

A total of 101 cases of chronic hepatitis (53 chronic active hepatitis and 48 chronic severe hepatitis ) were admitted to our department in 1982-1988. These patients were divided into five therapeutic groups. In chronic active hepatitis the satisfactory effect was achived with the total effective rate being 100%. In 48 cases of chronic severe hepatitis, the effective rate was 45.8%. The curative effect of chronic severe hepatitis was influenced by its complications, MOSF and the severity of damaged liver function.In order to improve the prognosis of chronic severe hepatitis, our opinion is that it is very important to prevent and treat its complication and MOSF. In addition to general treatment, fetal hepatic cells transfusion may be given lor a good therapeutic result.The current usage of fetal hepatic cells transfusion is discussed.