| 血清胱抑素C与老年高血压患者左室肥厚、慢性心力衰竭的关系 |
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| 引用本文： | 谢蒂立,金静,付明欢,张庆.血清胱抑素C与老年高血压患者左室肥厚、慢性心力衰竭的关系[J].实用医院临床杂志,2019(1):116-119. |
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| 作者姓名： | 谢蒂立 金静 付明欢 张庆 |
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| 作者单位： | 四川大学华西医院心内科;四川省医学科学院.四川省人民医院老年心血管科 |
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| 摘 要： | 目的分析老年高血压患者血清胱抑素C(Cys C)与左室肥厚、慢性心力衰竭的关系。方法纳入老年原发性高血压患者160例,依据超声心动图是否存在左室肥厚以及是否合并慢性心力衰竭,将其分为对照组(单纯原发性高血压组)80例、左室肥厚组48例、左室肥厚伴慢性心衰组32例。测定三组血清Cys C及血浆脑钠肽(BNP)水平,并分析血清Cys C与左室肥厚、心力衰竭指标的相关性。结果对照组、左室肥厚组、左室肥厚伴慢性心衰组患者舒张压比较差异无统计学意义(P> 0. 05),但收缩压依次升高,且血清Cys C、BNP水平依次显著升高,差异有统计学意义(P <0. 05)。同时对照组、左室肥厚组、左室肥厚伴慢性心衰组左室舒张末期内径(LVDD)、室间隔厚度(IVS)、左室后厚度(LVPW)各指标依次显著增加,LVEF依次显著降低,差异有统计学意义(P <0. 05)。相关性分析显示老年高血压患者血清Cys C水平与收缩压、LVDD、IVS、LVPW、BNP呈正相关,与LVEF呈负相关(P <0. 05)。结论老年高血压病患者血清Cys C浓度与左室肥厚、慢性心力衰竭具有显著的相关性。
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| 关 键 词： | 血清胱抑素C 高血压病 左室肥厚 慢性心力衰竭 |
The relationship among serum cystatin C,left ventricular hypertrophy and chronic heart failure in old patients with hypertension |
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| XIE Di-li,JIN Jing,FU Ming-huan,ZHANG Qing.The relationship among serum cystatin C,left ventricular hypertrophy and chronic heart failure in old patients with hypertension[J].Practical Journal of Clinical Medicine,2019(1):116-119. |
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| Authors: | XIE Di-li JIN Jing FU Ming-huan ZHANG Qing |
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| Institution: | (Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China;Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu 610072, China) |
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| Abstract: | XIE Di-li;JIN Jing;FU Ming-huan;ZHANG Qing(Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China;Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu 610072, China) |
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| Keywords: | Cystatin C Hypertension Left ventricular hypertrophy Chronic heart failure |
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