Abstract: | The action of ACTH on lipolysis was studied in the adipose tissue of rats with spontaneous and renal hypertension and also in normotensive rats of corresponding control groups. The sensitivity of the adipose tissue of SHR rats to ACTH was shown to be higher than in the normotensive control. Evidence was obtained that this increase in sensitivity is due to the state or quantity of intracellular calcium. In rats with renal hypertension no such increase in sensitivity of their adipose tissue to ACTH was found.Department of Pathomorphology, No. 4, Board, Ministry of Health of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR E. I. Chazov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 88, No. 7, pp. 23–26, July, 1979. |