化学共沉淀法制备葡聚糖四氧化三铁纳米颗粒

目的探讨葡聚糖包被的四氧化三铁纳米颗粒(DCIONP)的最佳配制条件,分析其主要物理性质。方法通过化学共沉淀法,配合适当的温度、pH值筛选葡聚糖、FeCl3.6H2O、FeCl2.4H2O的最佳质量比,反应一定时间后将产物离心、过滤,制备较纯净的葡聚糖包被的DCIONP,透射电镜和X射线粉末衍射法分析DCIONP的粒径和晶体结构。结果透射电镜及X射线衍射分析确定所制备的葡聚糖包被的磁性纳米粒子主要为Fe3O4晶体,氧化铁核心约为10 nm。结论本方法可操作性及实用性强,配制产物粒径小,性质稳定。

Preparing nanometer particle of dextran coated iron oxide nanoparticles by precipitation method

Objective To explore the best condition of constructing dextran coated iron oxide nanoparticles（DCIONP） by precipitation method,and to analyze its physical property.Methods The DCIONP was obtained by means of classical coprecipitation in dextran solution.The best proportion of quality of dextran,FeCl3·6H2O and FeCl2·4H2O was screened.Then the production was pured by centrifugating and filtering.Its size was determined by the transmission electron microscopy,and the crystal formation in DCIONP was measured by X-ray diffraction analysis.Results The iron size was 10 nm and the formation of Fe3O4 crystal in DCIONP was confirmed by the transmission electron microscopy and X-ray diffraction analysis.Conclusion The method has high manipuility and practicability,and the characterization of the prepared production is stable.