| 耐甲氧西林金黄色葡萄球菌临床感染分布及耐药性分析 |
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| 引用本文： | 弓艳娥,刘文恩. 耐甲氧西林金黄色葡萄球菌临床感染分布及耐药性分析[J]. 新乡医学院学报, 2011, 28(2): 202-204 |
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| 作者姓名： | 弓艳娥 刘文恩 |
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| 作者单位： | 1. 中南大学湘雅医院检验科,湖南,长沙,410008;长治医学院附属和平医院检验科,山西,长治,046000
2. 中南大学湘雅医院检验科,湖南,长沙,410008 |
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| 摘 要： | 目的了解山西省长治医学院附属和平医院耐甲氧西林金黄色葡萄球菌(MRSA)临床感染分布和耐药现状。方法常规进行细菌的分离培养和鉴定,采用纸片扩散法行药物敏感试验;采用头孢西丁纸片扩散法行MRSA菌株鉴定;采用双纸片扩散法(D试验)检测诱导型克林霉素耐药情况。结果耐药率>50.0%的有8种,其中青霉素、红霉素、克林霉素(包括2株D试验阳性株)、阿奇霉素、环丙沙星、左旋氧氟沙星、庆大霉素耐药率均达到100.0%。敏感率>50.0%的仅4种,其中万古霉素、替考拉宁敏感率为100.0%。MRSA对12种抗菌药物共有6种耐药表型,其中对青霉素、红霉素、克林霉素、阿奇霉素、环丙沙星、左旋氧氟沙星、庆大霉素、复方新诺明是其主要的耐药模式。38株MRSA中检测出对红霉素耐药、克林霉素敏感菌株共2株,D试验阳性株2株(100.0%)。结论 MR-SA菌株表现为多重耐药,耐药性有上升趋势。万古霉素仍是目前对抗NRSA感染的首选用药。
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| 关 键 词： | 耐甲氧西林金黄色葡萄球菌 感染 抗生素 耐药性 |
Distribution of clinical infection and analysis of drug resistance on methicillin resistant staphylococcus aureus |
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| GONG Yan-e,LIU Wen-en. Distribution of clinical infection and analysis of drug resistance on methicillin resistant staphylococcus aureus[J]. Journal of Xinxiang Medical College, 2011, 28(2): 202-204 |
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| Authors: | GONG Yan-e LIU Wen-en |
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| Affiliation: | GONG Yan-e1,2,LIU Wen-en1(1.Department of Clinical Laboratory of Xiangya Hospital of Central South University,Changsha 410008,Hunan Province,China,2.Department of Clinical Laboratory of Heping Hospital of Changzhi Medical College,Changzhi 046000,Shanxi Province,China) |
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| Abstract: | Objective To investigate the distribution and resistance of clinical isolates of methicillin resistant staphylococcus aureus(MRSA) from Heping Hospital of Changzhi medical college in Shanxi province.Methods Bacteria were isolated and identified routinely,drug susceptibility test was done by the disk diffusion method;MRSA was identified by cefoxitin disk diffusion method.Situation of inducible clindamycin resistance were detected by double disk diffusion(D test).Results There were 8 species in resistance rat... |
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| Keywords: | methicillin resistant staphylococcus aureus infection antibiotics drug resistance |
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