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| 电磁辐射对小鼠免疫功能的抑制作用 | |
| 引用本文： | 孟旭英,高春记,张怡堃,陈卫华,苏镇涛,周红梅.电磁辐射对小鼠免疫功能的抑制作用[J].军医进修学院学报,2009,30(2):215-217. |
| 作者姓名： | 孟旭英 高春记 张怡堃 陈卫华 苏镇涛 周红梅 |
| 作者单位： | 1. 解放军总医院血液科,北京,100853 2. 第二炮兵总医院,北京,100088 3. 军事医学科学院放射与辐射医学研究所,北京,100850 |
| 摘 要： | 目的：研究电磁辐射对小鼠免疫功能的影响。方法：288只BALB／c小鼠随机分为4组，分别接受频率为2856MHz、辐射剂量依次为0mW／cm^2、5mW／cm^2、10mW／cm^2、20mW／cm^2的辐射，辐射时间均为10min×6／d，连续照射5d。于照射后1h、1d、3d、7d、15d、30d检测外周血细胞计数、外周血T细胞亚群（CIM、CD8）、胸腺指数。结果：照射组在所有检测时间点与对照组（0mW／cm^2）相比白细胞计数及淋巴细胞计数均下降、CD4^＋／CD8^＋比值升高、胸腺指数下降（P〈0．05），至检测后期差异尤为显著，且免疫抑制作用随照射剂量增大而增强。结论：电磁辐射能抑制小鼠的免疫功能，且随着功率密度增大而抑制作用增强。 |
| 关 键 词： | 辐射 淋巴细胞 免疫 |
Inhibitory effect of electromagnetic radiation on immune function of mice |
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| MENG Xu-ying,GAO Chun-ji,ZHANG Yi-kun,CHEN Wei-hua,SU Zhen-tao,ZHOU Hong-mei.Inhibitory effect of electromagnetic radiation on immune function of mice[J].Academic Journal of Pla Postgraduate Medical School,2009,30(2):215-217. | |
| Authors: | MENG Xu-ying GAO Chun-ji ZHANG Yi-kun CHEN Wei-hua SU Zhen-tao ZHOU Hong-mei |
| Institution: | 1.Department of Hematology;Chinese PLA General Hospital;Beijing 100853;China;2.General Hospital of PLA Second Artillery Forces;Beijing 100088;3.Beijing Institute of Radiation Medicine;Beijing 100850;China |
| Abstract: | Objective:To study the effect of electromagnetic radiation on immune function of mice.Methods:Two hundred and eighty-eight BALB/c mice were randomly divided into four groups,which were exposed to 2 856 MHz electromagnetic radiation at the power density of 0mW/cm2,5mW/cm2,10mW/cm2 and 20mW/cm2,respectively,1h a day,for 5 consecutive days.The number of peripheral blood cells,the distribution of T-cell subpopulations(CD4 and CD8),and thymus index were detected 1h,1d,3d,7d,15d,and 30d,respectively,after electro... |
| Keywords: | radiation lymphocytes immunity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |