胰十二指肠切除术后功能性胃排空障碍的危险因素分析

目的研究影响胰十二指肠切除术后功能性胃排空障碍(FDGE)的危险因素及发生机理。方法采用病例对照研究,回顾性分析我院1994年～2006年间72例行胰十二指肠切除术患者的血液生化指标。结果72例中并发FDGE27例,发生率为37.5%。FDGE组患者与未发生FDGE组患者相比,血直接胆红素显著升高(P<0.05),白蛋白及总蛋白显著下降(P<0.01)。结论术前积极纠正低蛋白血症、高胆红素血症对预防FDGE的发生可能有积极意义。

Analysis of risk factors for functional delayed gastric emptying after pancreatoduodenectomy

Objective:To investigate the risk factors and mechanism of functional delayed gastric emptying (FDGE)after pancreatoduodenectomy(PD).Methods:In the case-control study of FDGE and non functional delayed gastric emptying(NFDGE) and a retrospective analysis was made on clinical data of 72 cases(1994-2006)after pancreatoduodenectomy.Results:Twenty seven cases were complicated with FDGE in 72 patients(37.5%)after operation and compared with the control NFDGE group,the blood direct bilirubin increased significantly(P<0.05) while albumin and total protein were declined obviously(P<0.01).Conclusion:Preoperative correct of hypoproteinemia and hyperbilirubinemia have possibly positive significance for prevention of FDGE.