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Effects of S-adenosyl methionine, ethanolamine, and their combination on lipid composition of rat brain in chronic alcohol intoxication
Authors:M I Selevich
Institution:(1) Department of Biomedical Problems of Narcology, Grodno State Medical Institute, Belarus
Abstract:Brain lipids are studied in rats with chronic alcohol intoxication after injection of S-adenosyl methionine, ethanolamine, and their combination. The levels of total lipids, phospholipids, and cardiolipin are increased and those of sphyngomyelin and cerebrosides-III decreased after a 14-day inhalation of ethanol. Combined administration of S-adenosyl methionine and ethanolamine in chronic alcoholization eliminated ethanol-induced shifts in concentrations of phospho- and glycolipid fractions in rat brain. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 4, pp. 398–400, April, 1998
Keywords:brain                      alcohol                      phospholipids                      glycolipids
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