| Hs—CRP、sCD40／CD40L和MMP-9在急性脑梗死中的作用 |
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| 引用本文： | 程立山,高朋杰,陈晶,宋宏杉,付锦,郭柳彩,宋亚彬,张立志,冯俊强. Hs—CRP、sCD40／CD40L和MMP-9在急性脑梗死中的作用[J]. 实用全科医学, 2010, 8(3): 321-322 |
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| 作者姓名： | 程立山 高朋杰 陈晶 宋宏杉 付锦 郭柳彩 宋亚彬 张立志 冯俊强 |
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| 作者单位： | 程立山,陈晶,宋宏杉,郭柳彩,宋亚彬,张立志,冯俊强(齐齐哈尔医学院第五附属医院,黑龙江省大庆油田总医院集团龙南医院神经内科十七病区,163453);高朋杰(黑龙江省大庆油田总医院集团油田总医院,163001);付锦(哈尔滨医科大学第二附属医院神经内科,150001) |
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| 摘 要： | 目的探讨高敏C-反应蛋白（High sensitivity C-reactive protein，Hs—CRP）、可溶性细胞表面分化抗原40及其配体（sCD40／CD40L）和基质金属蛋白酶-9（Matrix metallo proteinases-9，MMP-9）在脑梗死后斑块破裂局部和外周血含量的变化，破裂斑块和未破裂斑块炎性因子的变化是否存在差异，并与常规动脉造影组进行对比。方法急性脑梗塞动脉溶栓组和常规血管造影组分别取局部动脉血和外周静脉血进行上述炎症介质测定。结果动脉溶栓组炎症介质显著高于常规血管造影组，但动静脉相比较差异无统计学意义。结论Hs—CRP、sCD40／CD40L和MMP-9在急性脑梗死时明显高于正常，但局部血与静脉血无明显差异。
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| 关 键 词： | 脑梗死 高敏C-反应蛋白 可溶性细胞表面分化抗原40及其配体 基质金属蛋白酶 动脉溶栓 |
The Significance of Determination of Hs-CRP,sCD40/CD40L and MMP-9 in Patients with Acute Cerebral Infarction |
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| CHENG Li-shan,GAO Peng-jie,CHEN Jing,et al.. The Significance of Determination of Hs-CRP,sCD40/CD40L and MMP-9 in Patients with Acute Cerebral Infarction[J]. Applied Journal Of General Practice, 2010, 8(3): 321-322 |
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| Authors: | CHENG Li-shan GAO Peng-jie CHEN Jing et al. |
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| Affiliation: | CHENG Li-shan,GAO Peng-jie,CHEN Jing,et al.Department of Neurology,Longnan Hospital,the Fifth Affiliated Hospital of Qiqihaer Medical College,Daqing 163453,Heilongjiang,China |
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| Abstract: | Objective To investigate the changes of the peripheral blood high sensitivity C-reactive protein(Hs-CRP),soluble cell surface differentiation antigen 40 ligand(sCD40/CD40L) and matrix metal proteinase-9(MMP-9)in patients with the cerebral infarction before and after the mottling partially burst.Contrast was carried out with the conventional artery radiography group.Methods Determination of the above inflammation medium in the partial artery blood and the circumference venous blood was carried out in both th... |
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| Keywords: | Cerebral infarction Hs-CRP sCD40/CD40L MMP-9 |
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